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Pentobarbital, also known as Pentobarbital, is a fast-acting barbiturate. Large amounts of pentobarbital can cause respiratory failure and death. In the United States, this drug has been used to execute criminals. Rembeck (one of several manufacturers) does not allow sales in prisons or correctional facilities due to the death penalty.
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Large amounts of pentobarbital can be deadly. Used for human and animal euthanasia. In commercial euthanasia injection solutions it can be used alone or in combination with additives such as phenytoin.
The brand name of this drug is Nembutal, created by John S. Lundy, who used the drug in 1930 in the structural formula of the sodium salt Na (a common suffix for barbiturate). Nembutal is the Danish pharmaceutical company Lundbeck (now manufactured by Akorn Pharmaceuticals) and is the only injectable pentobarbital form approved for sale in the United States. Abbott’s Nembutal pentobarbital capsule has been widely abused and is called the “yellow jacket” on the street. Available in yellow capsules in concentrations of 50 and 100 mg.
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Suitable for the following strengths: 50 mg / ml; 100 mg; 18.2 mg / 5 ml; 120 mg; 60 mg; 50 mg; 200 mg; 30 mg; salt


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Pentobarbital, also known as pentobarbitone, is a short-acting barbiturate. In high doses, it causes death by respiratory arrest. Buy Nembutal online. Pentobarbital for sale. Nembutal for sale.
Again, pentobarbital is a short-acting barbiturate currently utilized to initiate and maintain medically induced coma, as well as for management of elevated intracranial pressure, particularly in the setting of traumatic brain injury. In addition, in the United States’ judicial system, the drug is utilized as a means of lethal injection in humans. Veterinarians administer pentobarbital most frequently for euthanasia purposes. Nembutal for sale.
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Euthanasia with Pentobarbital
Firstly, concentrated solutions of sodium pentobarbital are routinely used for the purposes of animal euthanasia because of rapid onset of action and efficacy. Solutions often contain greater than 300 mg/mL sodium pentobarbital. Intravenous injection in humans and animals results in rapid coma, respiratory depression, hypotension, bradycardia, and hypothermia. Nembutal for sale.
Consequently, these effects lead to prompt induction of asystole and death. In addition, while the majority of these agents are administered intravenously, they are also efficacious via oral, intramuscular, or intraperitoneal


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DESCRIPTION :

The barbiturates are nonselective central nervous system depressants which are primarily used as sedative hypnotics and also anticonvulsants in subhypnotic doses. The barbiturates and their sodium salts are subject to control under the Federal Controlled Substances Act (See “Drug Abuse and Dependence” section).
The sodium salts of amobarbital, pentobarbital, phenobarbital, and secobarbital are available as sterile parenteral solutions.
Barbiturates are substituted pyrimidine derivatives in which the basic structure common to these drugs is barbituric acid, a substance which has no central nervous system (CNS) activity. CNS activity is obtained by substituting alkyl, alkenyl, or aryl groups on the pyrimidine ring.
NEMBUTAL Sodium Solution (pentobarbital sodium injection) is a sterile solution for intravenous or intramuscular injection. Each mL contains pentobarbital sodium 50 mg, in a vehicle of propylene glycol, 40%, alcohol, 10% and water for injection, to volume. The pH is adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.
NEMBUTAL (pentobarbital) Sodium is a short-acting barbiturate, chemically designated as sodium 5-ethyl-5-(1-methylbutyl) barbiturate. The structural formula for pentobarbital sodium is:
NEMBUTAL® (Pentobarbital Sodium) Structural Formula Illustration The sodium salt occurs as a white, slightly bitter powder which is freely soluble in water and alcohol but practically insoluble in benzene and ether.
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Pentobarbital, also known as pentobarbitone, is a short-acting barbiturate. In high doses, it causes death by respiratory arrest. Buy Nembutal online. Pentobarbital for sale. Nembutal for sale.
Again, pentobarbital is a short-acting barbiturate currently utilized to initiate and maintain medically induced coma, as well as for management of elevated intracranial pressure, particularly in the setting of traumatic brain injury. In addition, in the United States’ judicial system, the drug is utilized as a means of lethal injection in humans. Veterinarians administer pentobarbital most frequently for euthanasia purposes. Nembutal for sale.
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Euthanasia with Pentobarbital
Firstly, concentrated solutions of sodium pentobarbital are routinely used for the purposes of animal euthanasia because of rapid onset of action and efficacy. Solutions often contain greater than 300 mg/mL sodium pentobarbital. Intravenous injection in humans and animals results in rapid coma, respiratory depression, hypotension, bradycardia, and hypothermia. Nembutal for sale.
Consequently, these effects lead to prompt induction of asystole and death. In addition, while the majority of these agents are administered intravenously, they are also efficacious via oral, intramuscular, or intraperitoneal routes.
Further, it has been reported that oral doses of sodium pentobarbital as little as 100 mg can induce hypnosis in adults, which substantially increases the lethality of unsecured concentrated veterinary formulations .
Other Uses

Firstly, as a sodium salt it has been used as a sedative and hypnotic in the short-term management of insomnia. Also, it has also been used for premedication in anesthetic procedures.
In addition, it is FDA-approved for the emergency control of certain acute convulsive episodes, for example:
• Those associated with status epilepticus
• Cholera
• Eclampsia
• Meningitis
• Tetanus
• Toxic reactions to strychnine or local anesthetics
Also, the other indications for pentobarbital include treatment of nonfatal submersion and traumatic/nontraumatic raised intracranial pressure.
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